ESTABLISHED SAFETY PROFILE
IN ADVANCED NSCLC

Selected ARs with a difference of ≥5% for all grades or ≥2% for Grade 3-4 toxicity between treatment groups
Established safety profile in Advanced Non-Small Cell Lung Cancer (NSCLC) - chart Established safety profile in Advanced Non-Small Cell Lung Cancer (NSCLC) - chart
  • a508 patients assessed in ABRAXANE/carboplatin-treated group.
  • b514 patients assessed in paclitaxel injection/carboplatin-treated group.
  • c513 patients assessed in paclitaxel injection/carboplatin-treated group.
  • dPeripheral neuropathy is defined by the MedDRA v14.0 SMQ neuropathy (broad scope).
  • MedDRA=Medical Dictionary for Regulatory Activities; SMQ=Standardized MedDRA Query.
  • a508 patients assessed in ABRAXANE/carboplatin-treated group.
  • b514 patients assessed in paclitaxel injection/carboplatin-treated group.
  • c513 patients assessed in paclitaxel injection/carboplatin-treated group.
  • dPeripheral neuropathy is defined by the MedDRA v14.0 SMQ neuropathy (broad scope).
  • MedDRA=Medical Dictionary for Regulatory Activities; SMQ=Standardized MedDRA Query.
  • Most Common Adverse Reactions

    ESTABLISHED SAFETY PROFILE
    IN ADVANCED NSCLC

    Common ARs (≥10%) for ABRAXANE + carboplatin observed at a similar incidence as with paclitaxel injection + carboplatin
    Common ARs (?10%) for ABRAXANE + carboplatin observed at a similar incidence as with paclitaxel injection + carboplatin
    Established safety profile in Advanced Non-Small Cell Lung Cancer (NSCLC) adverse reactions - chart Established safety profile in Advanced Non-Small Cell Lung Cancer (NSCLC) adverse reactions - chart
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Additional Information for Readers Provided by Celgene Corporation

The clinical trial described in this article served as the
basis for the approval for ABRXANE for Injectable Suspension.
The analyses contained in the article may differ from those in the package insert for ABRAXANE.

Please see Important Safety Information and Prescribing Information, including Boxed WARNING.

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